A Mini-Review on the Phytochemistry and Pharmacology of the Plant Carica Papaya L. (Caricaceae)

  • Clement Inkoto Liyongo Department of Biology, Faculty of Science, University of Kinshasa, Democratic Republic of the Congo
  • Colette Masengo Ashande Department of Environmental Sciences, University of Gbado-Lite, Gbado-Lite, Democratic Republic of the Congo
  • Clarisse Falanga Mawi Department of Biology, Faculty of Science, University of Kinshasa, Democratic Republic of the Congo
  • Blaise Membo wa Mbembo Department of Biology, Faculty of Science, University of Kinshasa, Democratic Republic of the Congo
  • Jean-Jacques Amogu Domondo Department of Biology, Faculty of Science, University of Kinshasa, Democratic Republic of the Congo
  • Mahendra Ilmi S Matondang Department of Biotechnology, FBIM, Universiti Sultan Zainal Abidin, Kuala Terengganu, Malaysia
  • Jean-Pierre Kayembe Kayembe Research Focus Area for Chemical Resource Beneficiation (CRB), Catalysis and Synthesis Research Group, North-West University, Potchefstroom 2522, South Africa
  • Pius Tshimankinda Mpiana Department of Chemistry, Faculty of Sciences, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
  • Koto-te-Nyiwa Ngbolua Department of Biology, Faculty of Science, University of Kinshasa, Democratic Republic of the Congo
Keywords: medicinal plant; carica papay; bioactivity; phytochemicals; phyto-drugs; democratic Republic of the Congo

Abstract

Medicinal plant is an important element of indigenous medical systems all over the world. The ethno botany provides a rich resource for natural drug research and development. Carica papaya is used in Traditional Medicine since a long time. Our investigations started by a search of relevant literature on the plant species. Databases such as Science direct, PubMed, Google Scholar and Scopus were used successively to retrieve the articles on C. papaya. The chemical structures of isolates compounds from this plant were drawn using ChemBioDraw Ultra 12.0 software package. Finally, bibliographical references were made using bibliographical software "Mendeley". Results show that the plant C. papaya contains various secondary metabolites, minerals and vitamins. The plant species is reported to possess various pharmacological properties like anti-oxidant, anti-inflammatory, antibacterial, anti-diabetic, anti-hyperlipidemic, larvicidal effects, etc. These pharmacological activities could due to the presence of various phytochemicals present in this plant species. The present review can therefore help inform future scientific research towards the development of novel drugs of relevance from C. papaya to combat various ailments including Sickle cell disease.

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Published
2020-09-15